Myhep

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What is MyHep ?

MyHep contains the active ingredient Sofosbuvir. It is a generic brand of anti-viral medication used to treat Hepatitis C virus. MyHep is manufactured by Mylan Pharmaceuticals. Sofosbuvir can help the immune system and the liver recover from an Hepatitis C infection. MyHep is an important addition to Mylan’s business in India and is sold as part of Hepato Care segment. The product is indicated for the treatment of chronic hepatitis C, a blood-borne infectious disease, as a component of a combination antiviral treatment regimen, MyHep (Sofosbuvir) is prescribed for the treatment of Hepatitis C in adults.

Product Description

Brand name: Myhep
Active Ingeridents(Generic Name) : Sofosbuvir
Company Name: Mylan Pharmaceuticals
Package: 28 Tablets
Strength : 400 Mg

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My hep 400mg tablet is used in the treatment of chronic hepatitis C virus (HCV) infection
My hep 400mg tablet works by lowering a load of hepatitis C virus in the body and removing the virus from the blood over a period of time.
Fatigue, Nausea, Headache, Insomnia (difficulty in sleeping), Anemia

Indication:

It is used for the treatment of hepatitis Cvirus (HCV) infection. It has been marketed since 2013. Compared to previous treatments, Sofosbuvir-based regimens provide a higher cure rate, fewer side effects, and a two- to four-fold reduced duration of therapy. Myhep (Sofosbuvir) allows most patients to be treated successfully without the use of peginterferon, an injectable drug with severe side effects. that is a key component of older drug combinations for the treatment of HCV. Myhep (Sofosbuvir) is used for the treatment of chronic hepatitis C, genotypes 1, 2, 3, and 4, in combination with pegylated interferon and ribavirin, or with ribavirin alone. It is also used in combination with the viral NS5a inhibitor ledipasvir in an interferon-free combination for the treatment of genotype 1 hepatitis C infection. Myhep (Sofosbuvir) is also used in HCV patients with an HIV coinfection. The treatment is based on a number of clinical trials, for example the ELECTRON trial which showed that a dual interferon-free regimen of Sofosbuvir plus ribavirin produced a 24-week post-treatment sustained virological response (SVR24) rate of 100% for previously untreated patients with HCV genotypes 2 or 3.

Mechanism of action:

Myhep(Sofosbuvir) contains oral nucleotide analog inhibitor of the hepatitis C virus (HCV) polymerase. The drug is a direct-acting antiviral agent and interferes straight with the HCV lifecycle, restraining the viral replication. It can be incorporated into HCV RNA by the NS5B polymerase and acts as a chain terminator. The drug is available for oral use in the form of 400mg tablets.

Dosage and Administration:

The recommended daily dose of Myhep (Sofosbuvir) is 400mg tablet to be taken once daily with or without food. Myhep (Sofosbuvir) should be used in combination with Ribavirin or in combination with Pegylated Interferon and Ribavirin for the treatment of CHC (Chronic Hepatitis C) in adults. It is highly advisable to administer the drug under strict medical supervision and advice.